What Is Collagen?
Collagen is the most abundant protein in your body and the structural foundation of your skin. It is what gives skin its firmness, elasticity, and that plump, smooth appearance associated with youth. Collagen works alongside elastin and hyaluronic acid to keep skin resilient, hydrated, and supported from within.
When collagen is abundant your skin bounces back, holds its shape, and maintains a smooth, even surface. When it starts to decline, and it will, the signs show up gradually and then all at once. Fine lines deepen. Skin loses its lift. Volume disappears from areas that used to look full. The jawline softens. The under eyes hollow.
Understanding when and how collagen loss happens is the first step to addressing it before it becomes harder to reverse.
Collagen Loss
In your 20s
Collagen production peaks in your early 20s and begins a slow, steady decline around age 25. You lose approximately 1 percent of your collagen per year from this point forward. Changes are subtle and most people do not notice anything yet, but this is actually the ideal time to start preventative treatments.
Signs of Collagen Loss
Fine lines and wrinkles that were not there before, deeper lines around the mouth including nasolabial folds and marionette lines, and expression lines that linger even when your face is at rest.
Hollowing under the eyes, flattening of the cheeks and temples, and a loss of the fullness that once gave your face a lifted, youthful shape.
Skin that feels looser than it used to, a softening of the jawline, the early appearance of jowling, and a general loss of the definition that once felt effortless.
Skin that looks dull or lacks its former glow, a thinner or more fragile feeling to the skin, and an overall loss of radiance and resilience that used to come naturally.
Cellenis Derma
The First Autologous Biostimulant Volumizer
Cellenis Derma is unlike any other treatment at Hollywood Skin. It is not a synthetic filler, it is not a foreign substance, and it does not add volume artificially.
Instead it harnesses the regenerative power of your own blood to stimulate your body's natural production of collagen, elastin, and hyaluronic acid from within.
The process begins with a simple blood draw. Your blood is processed to isolate platelet-rich plasma, a concentration of growth factors your body already produces.
That PRP is then activated and prepared into Cellenis Derma, the first and only autologous biostimulant volumizer available in the United States.
When injected into areas of volume loss and collagen depletion, Cellenis Derma signals your skin cells to begin regenerating. Collagen fibers rebuild. Elastin is restored. Hyaluronic acid production increases. Over the following weeks and months your skin becomes firmer, fuller, and more resilient, from the inside out.
Treatment areas include the under eyes, cheeks, chin, jowls, marionette lines, and nasolabial folds.
Results develop gradually over 4 to 8 weeks and continue to improve over several months. A series of treatments is typically recommended for optimal and lasting results.
Proof Is In The Pudding
Most volumizing treatments introduce something foreign into the body, synthetic hyaluronic acid, calcium hydroxylapatite, or poly-L-lactic acid. Cellenis Derma introduces nothing foreign. It is 100% derived from your own platelet-rich plasma, making it fully biocompatible with zero risk of allergic reaction.
FAQ
At what age does collagen loss begin?
Collagen production peaks in your early 20s and begins declining around age 25 at a rate of approximately 1 percent per year. Visible changes typically become noticeable in the mid to late 30s and accelerate significantly in the 40s and 50s.
Can you rebuild lost collagen?
Yes. While you cannot fully reverse collagen loss, treatments like Cellenis Derma and PRP therapy stimulate your body's own collagen production to meaningfully restore skin firmness, volume, and quality over time.
How long do biostimulators results last?
Results develop gradually over 4 to 8 weeks and continue to improve over several months. With a full series of treatments results can last 12 to 18 months or more. Individual results vary based on age, degree of collagen loss, and lifestyle factors.
Who is a good candidate for Cellenis Derma?
Cellenis Derma is ideal for patients experiencing volume loss, hollowing, or skin laxity who prefer a completely natural approach. It is also an excellent option for patients who want to avoid synthetic filler material or who are looking to improve overall skin quality alongside structural restoration. A consultation at Hollywood Skin will determine whether it is right for you.
How many Cellenis Derma treatments do I need?
A series of treatments spaced several weeks apart is typically recommended for optimal results. Your Hollywood Skin provider will build a personalized treatment plan based on your degree of collagen loss and your goals.